2型糖尿病足高危患者的踝肱指数与糖尿病足的关系

目的：对2型糖尿病足高危患者的踝肱指数和糖尿病足的发生率关系进行分析，同时对相关的危险因素进行探讨，以期对糖尿病足的发生早期采取有效的措施。方法对我院收治的已经确诊的438例2型糖尿病患者进行研究，其中391例为非糖尿病足组，47例为糖尿病足组，所有的患者都要进行糖化血红蛋白、总胆固醇、甘油三酯等生化资料、踝肱指数的检查，对两组的临床检查资料和不同踝肱指数组的糖尿病患者数的差异进行比较。结果两组患者踝肱指数与患者病程、收缩压、糖尿病肾病发生率、视网膜病变发生率呈负相关（P均＜0.01）；不同的踝肱指数和糖尿病足组的患病率比较，踝肱指数和糖尿病足组的患病率类似“U”型分布，踝肱指数＞1.31组中糖尿病足组的患者发病率为18.1%；0.9＜踝肱指数≤1.3组的发病率为26.0%；0.7＜踝肱指数≤0.9组的发病率为32.5%；0.5＜踝肱指数≤0.7组的发病率为47.6%；而踝肱指数≤0.5组中的糖尿病足患者发病率达到64.29%，各组患病率进行比较有明显的差异。结论踝肱指数和糖尿病足呈负相关，踝肱指数减低或是出现异常的升高能对早期糖尿病足的发生进行预测，对踝肱指数异常的糖尿病足高危患者要采用积极有效的干预措施。

Relationship between ankle brachial index and diabetic foot in patients at high risk of type 2 diabetic foot

ObjectiveTo understand the relationship between the ankle brachial index and diabetic foot in patients at high risk of type 2 diabetic foot and also discuss the related risk factors, in order to propose the effective measures for the early development of diabetic foot.Methods438 patients diagnosed as type 2 diabetes in this hospital were studied, including 391 patients with non-diabetic foot and 47 patients with diabetic foot.All patients received the examination of biochemical information of glycosylated hemoglobin,total cholesterol and triglyceride,as well as ankle brachial index. The clinical examination data of two groups and the difference in the number of diabetic patients with the different ankle brachial index were compared.Results Contraction of two group patients with ankle brachial index, pressure, course of disease in patients with diabetic nephropathy were positive, the incidence of retinopathy（P all〈0.01）,different ankle brachial index and the prevalence of diabetic foot group comparison, ankle brachial index and diabetic foot group the prevalence of similar ＂U＂ type of division, ankle brachial index greater than 1.31 in patients with diabetic foot group the incidence rate was 18.1%;the incidence of 0.9〈ABI≤1.3 group was 26%;the incidence of 0.7〈ABI≤0.9 group was 32.5%;the incidence of 0.5〈ABI≤0.7 group was 47.6%;and the ankle brachial index≤0.5 in the group of patients with diabetic foot disease incidence rate reached 64.29%,the prevalence rate were significantly different. Conclusion Ankle brachial index is negatively related to diabetic foot, ankle brachial index decrease or abnormal rise in early diabetic foot is predicted to occur, patients at high risk for diabetic foot ankle brachial index anomaly to adopt active and effective intervention measures.