左炔诺孕酮宫内节育器在中青年子宫腺肌症治疗中的应用分析

目的：探析左炔诺孕酮宫内节育系统在中青年子宫腺肌症治疗中的临床效果。方法选取我院就诊治疗子宫肌腺患者28例子宫腺肌患者,观察在放置左炔诺孕酮宫内节育器前后痛经、月经量、子宫体积、子宫内膜厚度、血清CA125、血清性激素水平的变化情况，比较治疗前后患者临床症状、激素水平的变化及不良反应。结果左炔诺孕酮宫内节育器放置12个月后，患者的痛经程度降低，子宫体积和子宫内膜厚度明显减小，CA125水平明显减低，与放置前相比差异有统计学意义（P＜0.05）。结论利用左炔诺孕酮宫内节育器可明显改善子宫腺肌症中痛经、月经量等临床症状，值得临床进一步研究进而推广。

Application analysis of levonorgestrel intrauterine device in treatment of young and middle-aged people with adenomyosis

Objective To explore the clinical effects of levonorgestrel intrauterine device in the treatment of young and middle-aged people with adenomyosis.Methods Twenty-eight patients with adenomyosis treated in our hospital were selected.Changes of the patients＇dysmenorrhea,menstrual blood volume,uterine volume, endometrial thickness,serum CA125 and serum sex hormone levels after placing the levonorgestrel intrauterine device were observed.The clinical symptoms,hormone level changes and adverse reactions of the patients before and after the placement of levonorgestrel intrauterine device were compared.Results After placing the levonorgestrel intrauterine device for 12 months, the patients＇dysmenorrhea degree decreased,uterine volume and endometrial thickness significantly reduced, and CA125 level significantly lowered,with significant differences to those before placing （P〈0.05）.Conclusion The application of levonorgestrel intrauterine device can significantly improve the clinical symptoms such as dysmenorrhea and menstrual blood volume in adenomyosis,thereby worthy of further clinical study and subsequent promotion.