Urinary excretion of MHPG and normetanephrine in attention deficit hyperactivity disorder |
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Authors: | Glen B. Baker Robert A. Bornstein Alan B. Douglass Jordyce C. Van Muyden Susan Ashton Teri-Lynn Bazylewich |
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Affiliation: | 1. Provincial Mental Health Advisory Council Research Unit, Department of Psychiatry, Mackenzie Centre, University of Alberta, T6G 2B7, Edmonton, Canada 2. Department of Psychiatry, Ohio State University, Columbus, OH
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Abstract: | Twenty-four-hour excretion (expressed per gram of creatinine) of the norepinephrine metabolites 3-methoxy-4-hydroxyphenylethylene glycol (MHPG) and normetanephrine (NME) was measured in children with attention deficit hyperactivity disorder (ADHD) and in normal subjects matched for age and education. In contrast to findings with Tourette syndrome patients, in the ADHD patients there was no significant difference in excretion of MHPG and NME from control values. |
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