| 细胞因子基因多态性与HBV相关肝细胞癌关系的研究进展 |
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| 引用本文： | 贝春华,仇小强. 细胞因子基因多态性与HBV相关肝细胞癌关系的研究进展[J]. 现代预防医学, 2011, 38(2): 334-337 |
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| 作者姓名： | 贝春华 仇小强 |
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| 作者单位： | 广西医科大学公共卫生学院流行病学教研室,南宁,530021 |
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| 摘 要： | 细胞因子作为宿主对炎症反应与免疫应答的重要介质,在宿主清除病毒的免疫应答以及抗肿瘤过程中发挥至关重要的作用。研究表明,一些细胞因子基因存在单核苷酸多态性,可导致不同个体之间细胞因子水平的差异,从而导致宿主免疫功能的差异,影响乙型肝炎病毒(HepatitisBvirus,HBV)感染者不同的临床表现和临床转归。本文综述了几种重要的细胞因子基因多态性与HBV感染相关肝细胞癌关系的研究。
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| 关 键 词： | 细胞因子 单核苷酸多态性:乙型肝炎病毒 肝细胞癌 |
ASSOCIATION OF CYTOKINE GENE POLYMOTPHISMS WITH HBV-RELATED HEPATOCELLULAR CARCINOMA |
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| BEI Chun-hua,QIU Xiao-qiang. ASSOCIATION OF CYTOKINE GENE POLYMOTPHISMS WITH HBV-RELATED HEPATOCELLULAR CARCINOMA[J]. Modern Preventive Medicine, 2011, 38(2): 334-337 |
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| Authors: | BEI Chun-hua QIU Xiao-qiang |
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| Affiliation: | BEI Chun-hua,QIU Xiao-qiang.(Department of Epidemiology,Guangxi Medical University,Nanning 530021,China) |
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| Abstract: | Cytokines acting as the mediator of inflammation reaction and immune response play an important role in the host immune response to eliminating virus and resisting tumor.According to some studies,cytokine genes single nucleotide polymorphism inducing different cytokine level in serum,various the host immune fuction,which can cause diversity of the clinical manifestation and outcome of patients with chronic hepatitis B virus infection.This review focus on evidence for a role for some important cytokine gene ... |
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| Keywords: | Cytokine Single nucleotide polymorphism Hepatitis B virus Hepatocellular carcinoma |
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