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恩度静脉滴注联合介入化疗栓塞治疗中晚期肝癌的临床研究
引用本文:王永中. 恩度静脉滴注联合介入化疗栓塞治疗中晚期肝癌的临床研究[J]. 现代预防医学, 2011, 38(2): 399-401
作者姓名:王永中
作者单位:河北医科大学第四医院放射科,石家庄,050011
摘    要:[目的]探讨恩度静脉滴注联合介入化疗栓塞治疗中晚期肝癌的临床疗效。[方法]本文将48例原发性肝癌患者随机分为观察组和对照组,其中观察组采用恩度静脉滴注联合介入化疗栓塞治疗,并与单独采用介入化疗栓塞治疗的对照组进行临床疗效比较。[结果]恩度联合TACE治疗肝癌的总有效率和AFP转阴率均较单纯采用TACE治疗的对照组高,差异有统计学意义(P﹤0.05)。恩度能有效抑制TACE术后肿瘤缺血缺氧引起的VEGF水平上升,抑制肿瘤血管生成,降低肿瘤的复发和转移,提高TACE治疗肝癌的疗效。另外,两组的不良反应相似,未出现心律失常、心电图改变、鼻出血等与恩度治疗相关副作用。[结论]恩度静脉滴注联合介入化疗栓塞治疗中晚期肝癌是一有效的治疗方法,值得在临床中推广和进一步研究。

关 键 词:恩度  经肝动脉化疗栓塞术  中晚期肝癌

ENDOSTAR INFUSION COMBINED WITH INTERVENTIONAL CHEMOTHERAPY AND EMBOLIZATION INTERVENTIONAL THERAPY IN TREATMENT OF ADVANCED LIVER CANCER
WANG Yong-zhong. ENDOSTAR INFUSION COMBINED WITH INTERVENTIONAL CHEMOTHERAPY AND EMBOLIZATION INTERVENTIONAL THERAPY IN TREATMENT OF ADVANCED LIVER CANCER[J]. Modern Preventive Medicine, 2011, 38(2): 399-401
Authors:WANG Yong-zhong
Affiliation:WANG Yong-zhong.(Department of Radiology,The Fourth Hospital of Hebei Medical University,Shijiazhuang 050011,China)
Abstract:[Objective]To investigate the involvement Endostar infusion chemotherapy and embolization in treatment of advanced liver cancer patients.[Methods]48 patients with primary liver cancer were randomly divided into two groups and the control group.The observation group was intervened by Endostar infusion chemotherapy and embolization interventional therapy,and compared with the control group which was intervened with the single chemotherapy and embolization interventional therapy.[Results]The total efficacy rat...
Keywords:Endostar  Hepatic artery chemoembolization  Advanced liver cancer  
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