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Solitary fibrous tumour of the liver with IGF-II-related hypoglycaemia. A case report
Authors:F. Famà  Yves Le Bouc  G. Barrande  A. Villeneuve  M. G. Berry  R. R. Pidoto  O. Saint Marc
Affiliation:3. Department of Human Pathology, University Hospital of Messina, Via Consolare Valeria, 1, 98100, Messina, Italy
5. Complesso Residenziale MITO, Residenza del Parco A/8, 98151, Camaro Superiore, Messina, Italy
4. APHP, H?pital Armand Trousseau, Explorations Fonctionnelles Endocriniennes, UPMC Paris VI, Inserm U.515, 26 Avenue Netter, 75571, Paris, France
2. Service Endocrinologie, Centre Hospitalier Régional Orléans, 14, Avenue de l’H?pital, 45 067, Orléans, France
1. Service Chirurgie Viscérale, Endocrinienne et Thoracique, Centre Hospitalier Régional Orléans, 14, Avenue de l’H?pital, 45 067, Orléans, France
Abstract:Introduction We report a rare case of solitary fibrous tumour (SFT) of the liver associated with non-islet cell tumour hypoglycaemia (NICTH), which caused a hypoglycaemic coma due to over-production of big-insulin-like growth factor-II. Discussion Although generally benign, SFTs are better characterised, lately due to Western blot, but less than 40 cases have been reported where the liver is the target organ. In only two benign cases has hypoglycaemia been a feature. Conclusion We report for the first time a demonstrable relationship between benign liver SFT and NICTH.
Keywords:Liver  Solitary fibrous tumour  IGF  Hypoglycaemia
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