Gonadotropin and steroid receptors as prognostic factors in advanced ovarian cancer: a retrospective study

Introduction  

Ovarian cancer is a chemosensitive tumour, but two thirds of women have a recurrence during the follow-up, even after an optimal surgical debulking followed by chemotherapy with a platinum and a taxane compound. Cytotoxic drugs are used in a second- or third-line setting but tumour progression is the rule. Also patients with the same histology achieve different outcomes in terms of survival. We decided to study gonadotropin and steroid receptors and to consider if these histological markers could select patients with different prognosis.