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头孢哌酮和中药治疗重症胰腺炎与IL-6、IL-8相关性的探讨
引用本文:金琦,黄朔,凌淑芳.头孢哌酮和中药治疗重症胰腺炎与IL-6、IL-8相关性的探讨[J].黑龙江医药科学,2004,27(4):36-37.
作者姓名:金琦  黄朔  凌淑芳
作者单位:佳木斯大学附属第一医院,黑龙江,佳木斯,154002;佳木斯铁路医院,黑龙江,佳木斯,154002
摘    要:目的:了解头孢哌酮与中药柴芩承气汤配伍治疗急性重症胰腺炎与IL-6、IL-8相关性。方法:酶联免疫吸附法。结果:头孢哌酮与中药柴芩承气汤配伍可以明显下调急性重症胰腺炎时IL-6、IL-8、血AMY水平,IL-6、IL-8与血AMY、胰腺湿重呈正相关,头孢哌酮钠 柴芩承气汤组的IL-6、IL-8与血AMY、胰腺湿重低于其余组,而其差异具有显著性。结论:头孢哌酮钠 柴芩承气汤是治疗急性重症胰腺炎的良好选择,柴芩承气汤在茵毒并治中作用显著。

关 键 词:急性重症胰腺炎  白细胞介素6、白细胞介素8  内毒素
文章编号:1008-0104(2004)04-0036-02
修稿时间:2004年5月12日

Different Antibiotics with Traditional Chinese Medicine, for the Treatment of SAP:correlation with IL-6 and IL-8
JIN Qi ,HUANG Shuo ,LING Shu-fang.Different Antibiotics with Traditional Chinese Medicine, for the Treatment of SAP:correlation with IL-6 and IL-8[J].Heilongjiang Medicine and Pharmacy,2004,27(4):36-37.
Authors:JIN Qi  HUANG Shuo  LING Shu-fang
Institution:JIN Qi 1,HUANG Shuo 1,LING Shu-fang 2
Abstract:Objective: To explore the relationship between SAP treated with Cefoperazone together with Traditional Chinese Medicine(TCM) and IL-6 and IL-8. Methods:Adopt the Enzyme-linked immunosorbent assay. Results: Cefoperazone matched with TCM decreased the levels of IL-6,IL-8 and AMY. The weigh of pancreas in the Cefoperazone+TCM group and Ciprofloxacin group was lower compared with other groups. Conclusion: Cefoperazone+Chinese Medicine is the best choice to treat SAP.Chaiqinchengqi Soup is important to release the injury by bacteria and endotoxemia.
Keywords:severe acute pancreatitis(SAP)  interleukin-6  interleukin-8  endotoxin
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