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血脂与脑梗死患者颈动脉粥样硬化的关系
引用本文:吴学兵,王琦,王宏,孙文化,钱雅琴,张欢,牛继华. 血脂与脑梗死患者颈动脉粥样硬化的关系[J]. 上海医学检验杂志, 2009, 0(1)
作者姓名:吴学兵  王琦  王宏  孙文化  钱雅琴  张欢  牛继华
作者单位:上海市松江区中心医院检验科;上海市松江区中心医院B超室;
摘    要:目的了解血脂与脑梗死患者颈动脉粥样硬化的关系。方法对344例脑梗死疑似患者进行三酰甘油(TG)、总胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、载脂蛋白A-I(apo A-I)、载脂蛋白B(apo B)、脂蛋白(a)[Lp(a)]检测,同时用计算机断层扫描(CT)、B超检测颈动脉病变。结果344例脑梗死疑似患者中有303例经临床及CT检查诊断为脑梗死,其余41例作为对照组。303例确诊患者中颈动脉管壁内膜-中层厚度(IMT)>0.9 mm或有斑块者206例,占68.0%;其余97例无病变,占32.0%。脑梗死患者LDL-C水平无论有无颈动脉病变均高于对照组(P<0.05)。无脑梗死的颈动脉粥样硬化患者apoA-I水平低于对照组(P<0.05)。结论LDL-C、apo A-I是发生脑梗死和颈动脉硬化病变重要的危险因素和诊疗的观察指标,B超检测颈动脉粥样硬化再结合血脂检查,对于脑血管疾病的预防、早期诊断、指导治疗以及观察疗效具有一定的临床价值。

关 键 词:血脂  脑梗死  颈动脉粥样硬化  

The relationship of the blood lipid and the carotid atherosclerosis of patients with cerebral infarction
WU Xuebing,WANG Qi,WANG Hong,SUN Wenhua,QIAN Yaqin,ZHANG Huan,NIU Jihua.. The relationship of the blood lipid and the carotid atherosclerosis of patients with cerebral infarction[J]. Shanghai Journal of Medical Laboratory Sciences, 2009, 0(1)
Authors:WU Xuebing  WANG Qi  WANG Hong  SUN Wenhua  QIAN Yaqin  ZHANG Huan  NIU Jihua.
Affiliation:1.Department of Clinical Laboratory;Shanghai Songjiang District Center Hospital;Shanghai 201600;China;2.B-Ultrasonography Section;China
Abstract:Objective To explore the relationship between the blood lipid and the carotid atherosclerosis in the patients with cerebral infarction.Methods The levels of triglycerides(TG),total cholesterol(TC),high density lipoprotein-cholesterol(HDL-C),low density lipoprotein-cholesterol(LDL-C),apolipoprotein A-I(apo A-I),apolipoprotein B(apo B),lipoprotein(a) in 344 patients with suspect cerebral infarction were determined and the carotid atherosclerosis was detected by computed tomography(CT)and B-ultrasonographic im...
Keywords:Blood lipid  Cerebral infarction  Carotid atherosclerosis  
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