A DNA-damaging sesquiterpene and other constituents from Frullania nisquallensis |
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Authors: | Kim Y C da S Bolzani V Baj N Gunatilaka A A Kingston D G |
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Affiliation: | Department of Chemistry, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061-0212, USA. |
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Abstract: | Bioassay-guided fractionation of an MeCOEt extract of Frullania nisquallensis Sull. has furnished a DNA-damaging sesquiterpene, costunolide (1), and two inactive compounds, a sesquiterpene (-)-frullanolide (2) and a tridepside tenuiorin (3). (13)C-NMR data of 3 are reported. |
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