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老年高血压患者动态脉压和脉压指数与颈动脉内膜中层厚度的关系
引用本文:许进,李鹏虹,陈佳,吴欣.老年高血压患者动态脉压和脉压指数与颈动脉内膜中层厚度的关系[J].心血管康复医学杂志,2011,20(6):504-507.
作者姓名:许进  李鹏虹  陈佳  吴欣
作者单位:福建省老年医院心内科,福建,福州市,350003
摘    要:目的:探讨动态脉压及其指数与高血压患者颈动脉内膜-中层厚度(IMT)的关系。方法:测量159例研究对象的24h动态血压,并计算动态脉压(平均收缩压-平均舒张压)及动态脉压指数(动态脉压/平均收缩压)。使用彩色多普勒超声检测颈动脉IMT。分析动态脉压指数与颈动脉IMT的相关性。结果:Pearson相关分析发现,颈动脉IMT与年龄(r=0.353)、平均收缩压(r=0.594)、平均舒张压(r=0.355)、动态脉压(r=0.855)、动态脉压指数(r=0.883)有良好的相关性(P均〈0.001)。进一步行多元逐步回归分析显示,颈动脉IMT与动态脉压及动态脉压指数具有显著线性关系(R2=0.789),动态脉压指数的标准回归系数(p=0.621)大于动态脉压的(p=0.284)。结论:动态脉压指数和动态脉压是评价颈动脉血管硬化的良好指标,动态脉压指数的价值更大。

关 键 词:高血压  血压监测  便携式  颈动脉  动脉硬化

Relationship among ambulatorypulse pressure, pulse pressure index and carotid intima-media thickness in aged patients with hypertension
XU Jin,LI Peng-hong,CHEN Jia,WU Xin.Relationship among ambulatorypulse pressure, pulse pressure index and carotid intima-media thickness in aged patients with hypertension[J].Chinese Journal of Cardiovascular Rehabilitation Medicine,2011,20(6):504-507.
Authors:XU Jin  LI Peng-hong  CHEN Jia  WU Xin
Institution:Department of Cardiology,Geriatric Hospital of Fujian Province,Fuzhou,Fujian,350003,China
Abstract:Objective: To study relationship among ambulatory pulse pressure (PP), pulse pressure index (PPI) and carotid intima--media thickness (IMT) in aged patients with hypertension. Methods: The 24h ambulatory blood pressures of 159 subjects were measured, and their ambulatory PP E(mean systolic blood pressure (SBP) mean diastolic blood pressure (DBP)] and ambulatory PPI (ambulatory PP/mean SBP) were calculated. Color Doppler ultra- sonography was used to measure carotid IMT. Relationship between ambulatory PPI and carotid IMT was analyzed. Results: Pearson correlation analysis indicated that carotid IMT was correlated with age (r=0. 353), mean SBP (r- 0.594), mean DBP (r=--0.355), ambulatory PP (r 0.855) and ambulatory PPI (r=0.883), P〈0.001 all. Multivariant gradual regressive analysis indicated that carotid IMT possessed significant linear correlation with ambulatory PP and ambulatory PPI (R2 =0. 789), and standardized regression coefficient t3 of ambulatory PPI (β=0. 621) was higher than that of ambulatory PP (β= 0. 284) . Conclusion: Ambulatory pulse pressure index and ambulatory pulse pressure are good indicators for evaluation of carotid arteriosclerosis, and value of ambulatory pulse pressure index is more than.
Keywords:Hypertensiom Blood pressure monitoring  Ambulatory  Carotid arteries  Arteriosclerosis
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