Derivatives of 2-Amino-1,2,3,4-Tetrahydronaphthalene,VIII.1) Isomerization of trans-2-Acetamido-3-hydroxy-5,8-dimethoxy-1,2,3,4-tetrahydronaphthalene and Hydrolysis of 5,8-Dimethoxy-2-methyl-3a,4,9,9a-tetrahydronaphth[2,3-d]oxazoline Hydrochloride

The isomerization of trans-2-acetamido-3-hydroxy-5,8-dimethoxytetraline (1) under the action of hydrogen chloride was investigated. Hydrolysis of 5,8-dimethoxy-2-methyl-3a,4,9,9a-tetrahydronaphth2,3-d]oxazoline hydrochloride (2) leads to cis-2-amino-3-hydroxy-5,8-dimethoxytetraline (3) .