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Studies on gliadin related peptides. I. Synthesis,purification and 1H n.m.r. characterization of the pentapeptide H-Tyr-(Gln)3-Pro-OH |
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| Authors: | V. PAVONE F. ROSSI P. PUCCI S. ANDINI L. FERRARA B. DI BLASIO C. PEDONE |
| Abstract: | The pentapeptide H-Tyr-(Gln)3-Pro-OH has been recently postulated to be the basic repetitive unit of a sequential polypeptide contained in wheat bread α-gliadins, which are believed to be toxic factors in coeliac disease, gluten-dependent enteropathy. Solid-phase synthesis, purification and 1H n.m.r. characterization in water solution of this peptide are described. |
| Keywords: | gliadins proton magnetic resonance solid-phase peptide synthesis |