胆汁反流性胃炎的临床研究

目的探讨莫沙必利联合泮托拉唑治疗胆汁反流性胃炎的临床疗效。方法将2011年1—12月期间我科收治的胆汁反流性胃炎患者84例随机分为两组,观察组与对照组各42例,给予观察组患者莫沙必利联合泮托拉唑,给予对照组患者莫沙必利。现比较两组患者的疗效。结果①两组患者的不良反应发生率相比差异无统计学意义（P〉0.05）。②观察组治疗效果显著优于对照组,两组比较差异有统计学意义（P〈0.05）。结论莫沙必利联合泮托拉唑治疗胆汁反流性胃炎具有不良反应发生率低,疗效确切等优点,该联合方案值得在临床上应用与推广。

Clinical study of bile reflux gastritis

Objective To explore the clinical therapeutic efficacy of mosapride combined with pantoprazole in the treatment of patients with bile reflux gastritis.Methods 84 patients with bile reflux gastritis who were admitted into our department from January 2011 to December 2011 were divided into 2 groups randomly.Observation group(n=42)received mosapride combined with pantoprazole,and control group(n=42)received single mosapride.Results There was no significant difference in overall complication rate between the 2 groups(P<0.05),and the therapeutic efficacy of the observation group was significantly better than that of the control group(P<0.05).Conclusion Mosapride combined with pantoprazole in the treatment of patients with bile reflux gastritis is of low overall complication rate and good therapeutic efficacy,so this procedure is worthy of being applied and popularized.