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Fulminant hepatitis and glomerulonephritis--a rare presentation of hepatitis A virus infection
Authors:Pal Radha B  Saha Pritam  Das Ira  Sinha Malay K
Institution:Department of Pediatrics, Medical College and Hospital, Kolkata, India. rbinod100@gmail.com
Abstract:Aim: We report a case of fulminant hepatitis and glomerulonephritis by Hepatitis A virus infection. Methods: We observed the patient’s clinical course and analyzed his data retrospectively. Results: The three‐year‐old boy presented with features of acute renal failure and stage 2 hepatic encephalopathy. Renal biopsy showed diffuse mesangioproliferative glomerulonephritis with immunoglobulin M and complement 3 deposition. After receiving supportive treatment for over 6 weeks, the hepatic and renal function became normal. Renal biopsy after 3 months was normal. Conclusion: Acute renal failure is a rare complication of Hepatitis A virus infection. Physicians should be aware of the potential renal involvement of Hepatitis A virus infection as the prognosis is not always favourable.
Keywords:Glomerulonephritis  Hepatic encephalopathy  Hepatitis A virus infection
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