| 42例膀胱癌及其癌旁组织中ras癌基因P~（21）蛋白的表达 |
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| 引用本文： | 李香云,金福顺,刘禄成,金明德. 42例膀胱癌及其癌旁组织中ras癌基因P~（21）蛋白的表达[J]. 吉林大学学报(医学版), 1996, 0(3) |
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| 作者姓名： | 李香云 金福顺 刘禄成 金明德 |
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| 作者单位： | 吉林省公主岭市医院 |
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| 摘 要： | 应用免疫组织化学技术（ＡＢＣ法），对４２例膀胱癌及癌旁组织中ｒａｓ癌基因Ｐ￣（２１）蛋白进行了检测。结果表明，膀胱癌组织中Ｐ￣（２１）蛋白阳性率为７３．８％，而４２例癌旁组织中Ｐ￣（２１）蛋白阳性率为１４．３％，Ｐ￣（２１）蛋白的阳性率随着病理分级、临床分期的升级增高，值得注意的是癌旁组织中Ｐ￣（２１）蛋白阳性者癌症易于复发，提示预后不良。
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| 关 键 词： | ras癌基因，P￣（21）蛋白，免疫组化，膀胱癌 |
Expression of ras oncogene P~(21)protein in bladder cancers and their surrounding tissues of 42 cases |
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| Li Xiangyun,Jin Mingde,Jin Fushun,et al. Expression of ras oncogene P~(21)protein in bladder cancers and their surrounding tissues of 42 cases[J]. Journal of Jilin University: Med Ed, 1996, 0(3) |
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| Authors: | Li Xiangyun Jin Mingde Jin Fushun et al |
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| Abstract: | P￣(21) protein of ras oncogene in bladder cancers and their surrounding tissues of 42 caseswas detected by immunohistochemical technique(ABC method).The results showed that P￣(21) proteinpositive rate in bladder cancer and its surrounding tissues was 73.8%and 14.3%respectively.P￣(21) pro-tein enhanced with the increasing of pathological grade and clinical stage in bladder cancer.The posi-tive cases of P￣(21) in surrounding tissues has worse prognosis. |
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| Keywords: | ras oncogene P￣(21) protein immunohistochemistry bladder cancer |
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