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羚羊感冒胶囊的质量标准研究
引用本文:郑莉,宋英. 羚羊感冒胶囊的质量标准研究[J]. 中国药房, 2011, 0(31): 2952-2954
作者姓名:郑莉  宋英
作者单位:成都中医药大学附属医院药剂科;
摘    要:目的:建立羚羊感冒胶囊的质量标准。方法:考察羚羊感冒胶囊的性状、显微特征,用薄层色谱(TLC)法对方中牛蒡子、桔梗、甘草、金银花进行定性鉴别,用高效液相色谱法对金银花中绿原酸进行含量测定。结果:显微特征明显;TLC斑点清晰、分离度好;绿原酸进样量在0.07952~0.99400μg范围内与峰面积积分值呈良好线性关系(r=0.9999),平均加样回收率为100.6%,RSD=1.41%(n=6)。结论:所用方法操作简便、专属性强,所建标准可用于羚羊感冒胶囊的质量控制。

关 键 词:羚羊感冒胶囊  质量标准  性状  定性鉴别  定量分析

Quality Standard of Lingyang Ganmao Capsules
ZHENG Li,SONG Ying. Quality Standard of Lingyang Ganmao Capsules[J]. China Pharmacy, 2011, 0(31): 2952-2954
Authors:ZHENG Li  SONG Ying
Affiliation:ZHENG Li,SONG Ying(Dept.of Pharmacy,The Affiliated Hospital of Chengdu University of Traditional Chinese Medicine,Chengdu 610072,China)
Abstract:OBJECTIVE:To establish the quality standard of Lingyang ganmao capsule.METHODS:The character and microscopic characteristics of Lingyang ganmao capsules were studied.TLC method was used to identify Arctium lappa,Platycodon grandiflorum,Glycyrrhiza uralensis and Lonicera japonica in it.The content of chlorogenic acid in L.japonica was determined by HPLC.RESULTS:The microscopic characters and the TLC spots were clear.The calibration curve of chlorogenic acid was linear within the range of 0.079 52~0.994 00 μg(r=0.999 9) with an average recovery of 100.6%(RSD=1.41%,n=6).CONCLUSION:The method is convenient and specific.It can be used for the quality control of Lingyang ganmao capsule.
Keywords:Lingyang ganmao capsule  Quality standard  Character  Qualitative identification  Quantitative analysis  
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