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Severe acute haemorrhagic liver failure in a neonate with a favourable spontaneous outcome
Authors:Madeleine Cavet  Marie Balu  Catherine Garel  Delphine Mitanchez  Sylvain Renolleau  Marie Alexandre  Danièle Pariente  Hubert Ducou le Pointe
Affiliation:1.Service de Radiologie, H?pital d’enfants Armand-Trousseau,Université Pierre et Marie Curie Paris VI,Paris Cedex 12,France;2.Service de Néonatologie, H?pital d’enfants Armand-Trousseau,Université Pierre et Marie Curie Paris VI,Paris,France;3.Service de Réanimation, H?pital d’enfants Armand-Trousseau,Université Pierre et Marie Curie Paris VI,Paris,France;4.Service de Radiologie Pédiatrique,H?pital de Bicêtre,Paris,France
Abstract:Acute liver failure in neonates is rare and is frequently associated with an unfavourable outcome. There is no curative treatment other than liver transplantation. Screening for viral, metabolic, toxic or vascular disease is essential to assess the prognosis and to guide specific treatment. Hepatic haemorrhage in neonates is often associated with bacterial infection, trauma and coagulopathies. We present a unique case of neonatal acute liver failure and multifocal massive haemorrhagic intrahepatic lesions of traumatic origin, documented by US and MRI. The patient made a spontaneous recovery. Clinical, biological and imaging outcome was excellent despite the apparent severity of the initial features. The only possible aetiology was a difficult caesarean delivery for mild fetal macrosomia.
Keywords:Liver  Haemorrhage  Trauma  Neonate
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