朝阳市某专科学校新生乙肝疫苗接种情况调查分析

目的了解辽宁省朝阳市师范高等专科学校3年制大专2008届1475名新入校学生乙肝疫苗的接种情况，为有针对性的制定乙肝预防控制策略提供依据。方法选择2008届3年制大专新入校的1475名学生作为研究对象，进行乙肝疫苗接种情况问卷调查和乙肝两对半检查；对HBV5项指标（HBsAg、抗-HBs、HBeAg、抗-HBe、抗HBc）检查均为阴性、肝功能检查为正常的新生按照“0、1、6”方案，进行乙肝疫苗接种。对1个月后检测抗-HBs为阴性的学生，实施增加剂量（10μg／ml）按照“0、1、2”方案进行接种，并对接种效果进行统计分析。结果1475名新入校学生的乙肝疫苗接种率为74．03％，HBsAg阳性率为5．67％。420名新生疫苗初次接种1个月后，抗-HBs阳转率为76．43％，男生与女生阳转率差别不显著（P〉0．05）。对检验抗-HBs为阴性的99名新生，采取增加剂量第2次复，阳转率为100％。在问卷调查中，部分新生对乙肝的危害认识不够，缺乏自觉接种的意识。结论乙肝疫苗接种是防止HBV感染的有效方法，疫苗复种是目前有效，切实可行的解决乙肝疫苗无应答问题的手段。

Analysis of hb vaccine vaccination and immunity effect among the freshemn in chaoyang university

Objective The aim of this study was to investigate the rate of hepatitis B vaccine among the freshmen of three-years and the immunity effect after vaccination, and to provide reference for further prevention and control. Methods 1475 freshmen of three-years were collected,and investigated about hepatitis B vaccinated, and detected the the marker(HBsAg,anti-HBS, HBeAg anti-HBe and Anti-HBc) of hepatitis B; the fivetargets of HBV were showed to be negative, and normal liver function were immunized with hepati...