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局部晚期胃癌术后辅助腹腔化疗的临床观察
引用本文:胡宇,蔡鼎男.局部晚期胃癌术后辅助腹腔化疗的临床观察[J].泰山医学院学报,2011,32(8):606-608.
作者姓名:胡宇  蔡鼎男
作者单位:1. 莆田市第一医院肿瘤内科,福建莆田,351100
2. 莆田学院附属医院,福建莆田,351100
摘    要:目的探讨局部晚期胃癌术后辅助腹腔化疗的疗效和不良反应。方法采用对比研究方法,对我院2006年1月至2009年12月200例局部晚期胃癌术后患者随机分为腹腔灌注化疗联合静脉化疗组(治疗组n=87)和单纯静脉化疗组(对照组n=113),观察两组的生存时间和化疗的毒副反应。结果两组随访,腹腔化疗联合静脉化疗组中位生存时间分别为28.00个月,单纯静脉化疗组中位生存时间为11.24个月,局部晚期胃癌术后加用腹腔化疗组较单纯静脉化疗组延长了生存时间,不良反应无显著差异。结论局部晚期胃癌术后静脉联合腹腔化疗,较单纯静脉化疗,延长生存时间,疗效较好,且耐受性较好。

关 键 词:胃癌  腹腔化疗  生存分析

Clinical observation of locally advanced gastric cancer postoperative adjuvant intraperitoneal chemotherapy
HU Yu,CAI Ding-nan.Clinical observation of locally advanced gastric cancer postoperative adjuvant intraperitoneal chemotherapy[J].Journal of Taishan Medical College,2011,32(8):606-608.
Authors:HU Yu  CAI Ding-nan
Institution:HU Yu1 CAI Ding-nan2(1.The First Hospital of Putian City,Putian 351100,China,2.Dept.of General Medicine,Putian University,China)
Abstract:Objective: To discuss the efficacy and adverse reaction of locally advanced gastric cancer postoperative adjuvant intraperitoneal chemotherapy.Methods: A comparative research method was used.200 cases of local advanced gastric cancer patients in our hospital from 2006 January to 2009 December were randomly divided into abdominal cavity perfusion chemotherapy combined with venous chemotherapy(treatment group,n=87) and intravenous chemotherapy group(control groupn=113),and the survival time and the toxicity o...
Keywords:gastric canaer  intraperitoneal chemotherapy  survival analysis  
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