Central pontine and extra-pontine myelinolysis in an alcoholic patient without hydro-electrolyte disturbances: case report |
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Authors: | Germiniani Francisco Manoel B Roriz Mauricio Nabhan Samir K Teive Helio A G Werneck Lineu C |
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Institution: | Servi?o de Neurologia, Departamento de Clinica Medica, Hospital de Clinicas da Universidade Federal do Parana, Curitiba, PR, Brasil. |
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Abstract: | Central pontine myelinolysis (CPM) and extra-pontine myelinolysis (EPM) are different presentations of a demyelinating disorder of the brain more commonly associated with rapid correction of hyponatremia, spastic tetraparesia and pseudo-bulbar palsy. There are in the literature a few cases of CPM/EPM in patients without electrolyte disturbances. We report the case of a 39 year-old man with severe alcoholism, who presented with spastic tetraparesis and palsy of several cranial nerves, associated with lesions in the magnetic resonance compatible with CPM/EPM. The patient had a good follow-up after pulse therapy with corticosteroids. |
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