蛇床子水煎剂对D-半乳糖衰老小鼠脑和肝组织中谷胱甘肽过氧化物酶,丙二醛活性的影响

为探讨蛇床子水煎剂的抗氧化机制，本实验采用D－半乳糖衰老小鼠，灌喂蛇床子水煎剂，分别于15，30，45d处死，测定小鼠脑和肝组织谷胱甘肽过氧化物酶（GSH－Px）丙二醛（MDA）的活性．实验结果表明：与D-半乳糖衰老模型组比较，蛇床子水煎剂能明显提高衰老小鼠脑和肝的GSH－Px活性，明显降低MDA的含量．提示蛇库于水煎剂对衰老小鼠有抗氧化作用，可延缓小鼠脑和肝的衰老．

Effect of fructuscnidii decoction on GSH-Px and MDA activity of brain and liver tissue in D-Galacose-induced mouse aging model

To probe the machinism of antioxidation of fructUscnidii decoction, D-galactose-induced mouse aging model was used.Given fructuscnidii decoetion for 15 days, 30 days and 45 days repectively, the activities of glutathionre pexoxidase (SSH-Px) and malondialhy dride (MDA) in brain and liver were measured. The results showed that compared with aging model group fructuscnidii decoction increased the activities of GSH-Px and decreased the contcht of MDA obviously, suggesting fructuscnidii decoction might raise antioxidation activity of mouse brain and liver, and delay aging.