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| 诺森（注射用泮托拉唑钠）治疗上消化道出血疗效观察 | |
| 引用本文： | 王曾铎,张兆文,李增灿,孙吉玲,刘铁夫,陈淑香,宋光,任旭,朱春兰.诺森（注射用泮托拉唑钠）治疗上消化道出血疗效观察[J].中国医院用药评价与分析,2001,1(1):37-38. |
| 作者姓名： | 王曾铎 张兆文 李增灿 孙吉玲 刘铁夫 陈淑香 宋光 任旭 朱春兰 |
| 作者单位： | 1. 哈尔滨医科大学附属第二医院, 2. 哈尔滨医科大学附属第一医院, 3. 黑龙江省医院, |
| 摘 要： | 目的验证与评估诺森（注射用泮托拉唑钠）治疗上消化道出血的临床疗效和安全性。方法采用随机分组、平行对照、多中心同步试验方法，对160例各种类型胃炎、消化性溃疡、肝硬化合并胃粘膜病变所致上消化道出血患者，分别应用诺森针剂40mg，qd，静滴3d～5d；奥美拉唑40mg，qd，静滴3d～4d，观察两组药物止血效果及不良反应。结果诺森组与奥美拉唑组总有效率分别为96.67％与95.00％，两组间疗效无显著性差异（P>0.05）；不良反应发生率分别为6.67％和6.67％，两组间无显著性差异（P>0. |
| 关 键 词： | 诺森 上消化道出血 疗效 |
| 文章编号： | 2001－01－0037－02 |
| 修稿时间： | 2001年1月15日 |
Observation of the Therapeutic Effect of Pantoprazole on Hemorrhage of Upper Digestive Tract |
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| WANG Zengduo,ZHANG Zhaowen,LI Zengcan,SUN Jiling.Observation of the Therapeutic Effect of Pantoprazole on Hemorrhage of Upper Digestive Tract[J].Evaluation and Analysis of Drug-Use in Hospital of China,2001,1(1):37-38. | |
| Authors: | WANG Zengduo ZHANG Zhaowen LI Zengcan SUN Jiling |
| Abstract: | OBJECTIVE:To verify and evaluate the effect and safety of pantoprazole in treating hemorrhage of upper digestive tract. METHODS:Using randomized group sampling,paired control and multicenter study,the hemostatic effects and adverse reactions of pantoprazole(PZ)and omeprazole (OZ) were observed in 160 cases who received PZ(40mg im qd and iv 3-5 days) or OZ (40mg im qd and iv 3-4 days) .RESULTS: The effective rates of PZ and OZ group were 96.67% and 95.00% respectively without difference between two groups(P>0.05) .The rates of ARDs of PZ and OZ group were 6.67% and 6.67% respectively without difference between two groups. The ARDs were mild.There were no significant changes of hematopoietic, hepatic and renal functions and routine urine examination in both groups after treatment .CONCLUSION: PZ shows satisfactory therapeutic effect on hemorrhage of upper digestive tract and no marked ARDs.It is worth extending and applying. |
| Keywords: | pantoprazole hemorrhage of upper digestive tract therapeutic effect |
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