气相色谱法测定维生素E软胶囊含量的不确定度评定

目的:探讨气相色谱法测定维生素E含量的不确定度评定方法。方法:通过分析测量过程,确定并简化不确定度来源;利用气相色谱法测定维生素E的方法验证数据及经验数据,通过统计学方法,量化不确定度分量;计算合成不确定度和扩展不确定度。结果:气相色谱法测定维生素E的扩展不确定度为3.6%。结论:测量不确定度可用于维生素E的标准限量的制定;测量不确定度的评定方法的确立建立对于药品、保健品、食品及化妆品质量标准的研究具有一定意义。

GC evaluation of measurement uncertainty for the determination of vitamin E soft cream

Objective:To set out the procedure for estimation of measurement uncertainty for the determination of Vitamin E by GC.Methods:Each uncertainty component was evaluated with respect to the significance of its contribution to the overall measurement uncertainty and was expressed as standard uncertainty.All the standard uncertainties were then combined according to the appropriate rules to give a combined standard uncertainty and an expanded standard uncertainty.Results:The expanded standard uncertainties for the GC determination of Vitamin E is 3.6%.Conclusion:Measurement uncertainty is applicable to set the limit of the Vitamin E.The establishment of the methodology for the evaluation of measurement uncertainty is important to the studies of Drugs,Health Products,Foods and cosmetic standards.