呼吸系统症状为主的胃食管反流病48例临床分析

目的:观察以呼吸系统症状为主的胃食管反流病(GERD)患者酸反流事件和基础下食管括约肌压力(LESP)的关系。方法:对48例以呼吸系统症状为主的GERD患者的临床特点进行分析,测定食管内PH值和食管压力。结果:有呼吸系统症状的GERD患者,其食管下括约肌功能有所改变;质子泵抑酸剂和促胃肠道动力药物治疗前后24h食管反流变化和食管内pH值变化均有显著性差异;治疗后呼吸系统症状得到改善。结论:胃食管反流可以作为独立原因引起呼吸道病症状,抑酸抗反流治疗对胃食管反流相关的呼吸系统症状有较好的近期疗效。

Clinical Analysis of 48 Gasfroesophageal Refulux Disease Patients With Respiratory Symptoms

Objective: To study the relationship between the acid-reflux events of GERD patients with respiratory symptoms and basic LESP.Methods: To analyse the clinical presentations, and measure the pH and pressure in esophagus of 48 GERD patients with main respiratory complaints.Results: Abnormal alteration of the function of LES in GERD patients was observed. The esophageal acid-reflux and pH in esophgus changed significantly after PPI and anti-reflux therapy for 24 h. The respiraty symptioms were alleviated. Conclusions: GERD may be an independent cause of respiratory symptoms which could be alleviated significantly by anti-acid therapy and anti-reflux therapy in a short time.