高压氧治疗糖尿病周围神经病变疗效研究

目的：探讨高压氧对糖尿病周围神经病变的疗效。方法：给38例糖尿病周围神经病变的患者进行高压氧治疗，在0．15mpa下行面罩间歇吸氧，即吸氧30min，换空气5min，如此反复2次，总吸氧60min，每天一次，10次为一疗程，中间休息5d，连续三个疗程，并采用体感诱发电位（SEP）作为诊断和观察神经传导障碍改善的指标，治疗前后均作了SEP对照 。结果：经高压氧治疗后糖尿病周围神经病变的症状和体征均有不同程度的改善，显示正中神经，胫神经各波峰潜伏时的缩短，提示神经传导有改善，显效68％，有效32％，总有效率100％，结论：高压氧是治疗糖尿病周围神经病变的一种安全，有效的措施。

Reaserch of treatment of hyperbaric oxygen on diabetic peripheral neuropathy

Objective : To discuss the effect of hyperbaric oxygen on diabetic peripheral neuropathyz. Methods : 38 patients of diabetic peripheral neuropathy were treated with hyperbaric oxygen.Under 0.15mpa,using face mask,the patients were treated with intermihent oxygen therapy,that is inhalating oxygen for30 minutes ,then changing to air for 5 minutes and repeated like this for two tilmes.Totat inhalating oxygen time is 60minutes.One time a day.Ten times is one treatmentcourse.Three continuous courses were given with 5 days resting between the treatlment courses.Body-sensory evoked potential tSEP) was used as the index to diagnosis and improvement of nerve conduction disfunction.SEP was controlled before and after treatment.Results: After treatment,the symptoms and signs to diabetic peripheral neuropathy improved differently.Latent time of wave crests of tibial nerve and imedian nerve had been shortened.It showed the improvement of nerve conduction,the significant effective rate is 68% and effective rate is 32%.Total effective rate is 100%.Conclusion:Hyperbaric oxygen-action on diabetic peripheralneuropathy is a safe and effective method.