广州市学龄儿童红细胞分布宽度与血压水平的相关性

探讨广州市6~11岁学龄儿童红细胞分布宽度(red blood cell volume distribution width,RDW)与血压水平的相关性,为有效预防控制学龄儿童高血压提供参考.方法 采用整群抽样的方法抽取广州市6~11岁学龄儿童6 188名,对调查对象进行血压测量和静脉全血细胞分析,分别获得收缩压、舒张压、红细胞数量、血红蛋白和RDW等指标,采用Pearson相关分析和逐步线性回归等方法进行统计分析.结果 广州市6~11岁学龄儿童RDW中位数为13.3%,男生(13.4%)高于女生(13.3%) (Z=8.609,P<0.01);收缩压的中位数为100 mmHg,舒张压中位数为64 mmHg;高血压和高血压前期组学龄儿童RDW高于血压正常组的儿童(H=15.400,P<0.05).Pearson相关分析显示,RDW与收缩压和红细胞数均呈正相关(r值分别为0.044,0.465,P值均<0.01),与血红蛋白呈负相关(r=-0.219,P<0.01).多元线性逐步回归显示,收缩压是RDW的影响因素之一(B=0.002,P=0.008).结论 RDW在高血压和高血压前期学龄儿童中增高,且与收缩压存在关联.

Relationship between red blood cell distribution width and school pressure among age blood children in Guangzhou city

Objective To analyze the relationship between red blood cell distribution width(RDW) and blood pressure level among children aged 6-11 years,and to provide a reference for effectively preventing and controlling high blood pressure among children of school age.Methods Cluster sampling method was used to select 6 188 school-aged children aged 6-11 years in Guangzhou,and their systolic blood pressure and diastolic blood pressure were measured by blood pressure measurement,while Red blood cell distribution width,hemoglobin,red blood cell count,and hematocrit was calculated by Friedewald equation.Pearson's correlation coefficient and multiple regression were used to analyze the relationship between RDW and blood pressure level.Results The median RDW was 13.3%,and boys(13.4%) got a higher median RDW than girls(13.3%) (Z=8.609,P<0.01).The median systolic blood pressure was 100 mmHg and the median diastolic blood pressure was 64 mmHg.Compared with normotension group,pre-hypertension group and hypertension group had higher RDW levels (H=15.400,P< 0.05).RDW and RBC were positively correlated to systolic blood pressure in Pearson correlation analysis(r=0.044,0.465,P<0.01),while hemoglobin was negatively correlated (r=-0.219,P<0.01).And multiple regression analysis showed that high systolic blood pressure was one of the risk factors of RDW(B=0.002,P =0.008).Conclusion RWD level increased in school-aged children with hypertension or pre-hypertension,and it was positively related to systolic blood pressure.