| 正交试验优选宁心痛颗粒的提取工艺 |
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| 引用本文： | 王志庆. 正交试验优选宁心痛颗粒的提取工艺[J]. 现代中药研究与实践, 2007, 21(4): 57-58 |
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| 作者姓名： | 王志庆 |
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| 作者单位： | 南京脑科医院,江苏,南京,210029 |
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| 摘 要： | 目的优选宁心痛颗粒最佳提取条件。方法以葛根总黄酮为考察指标,设计了L9(33)正交试验。结果最佳提取工艺为A1B2C2,即加醇量为药材的8倍,醇浓度(%)为70%,提取时间为2h。此条件下提取物葛根总黄酮含量可达10mg/g。结论优选的工艺条件可为新药研究和工业化生产提供参考。
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| 关 键 词： | 宁心痛颗粒 葛根 总黄酮 正交试验 |
| 文章编号： | 1673-6427（2007）04-0057-02 |
| 收稿时间： | 2007-03-07 |
| 修稿时间： | 2007-03-07 |
Optimizing Extraction Technics for Ningxintong Granules by Orthogonal Test |
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| WANG Zhi-qing. Optimizing Extraction Technics for Ningxintong Granules by Orthogonal Test[J]. Research and Practice on Chinese Medicines, 2007, 21(4): 57-58 |
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| Authors: | WANG Zhi-qing |
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| Affiliation: | Nanjing Brain Hospital, Nanjing 210029, China |
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| Abstract: | Objective To optimize the optimum extraction process for Ningxintong granules. Methods Orthogonal test was used to optimize the extraction process and the content of total flavonoids was chosen as the evaluating index. Results The best extraction technology was A1B2C2,that meant the raw drug materials were extracted twice, 2 h for each time by adding 8 times of 70% alcohol. Conclusion The optimum extraction process condition of Ningxintong granules provides scientific base for large producton. |
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| Keywords: | Ningxintong granules extraction process orthogonal test |
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