| 阻断致瘤病毒复制的抗肿瘤药物筛选策略 |
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| 引用本文： | 叶茂,曹亚. 阻断致瘤病毒复制的抗肿瘤药物筛选策略[J]. 中国肿瘤, 2003, 12(11): 652-655 |
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| 作者姓名： | 叶茂 曹亚 |
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| 作者单位： | 中南大学湘雅医学院肿瘤研究所,湖南,长沙,410078 |
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| 摘 要： | 许多病毒与人类恶性肿瘤的发生有关，阻断病毒与靶细胞的结合和融合、干扰病毒的复制和表达，抑制与病毒复制有关的酶等多个环节，将为抗肿瘤药物的筛选提供相关策略。
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| 关 键 词： | 致瘤病毒 肿瘤 抗肿瘤药物 病毒复制 酶 |
| 文章编号： | 1004-0242(2003)11-0652-04 |
| 修稿时间： | 2003-05-23 |
The Strategy for Screening of Antitumor Drug Based on Blocking Viral Replication |
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| YE Mao,CAO Ya. The Strategy for Screening of Antitumor Drug Based on Blocking Viral Replication[J]. CHINA CANCER, 2003, 12(11): 652-655 |
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| Authors: | YE Mao CAO Ya |
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| Abstract: | Many kinds of viruses related to the occurrence of human malignancies.Some strategies,such as blocking the coalition and fusion of virus with target cell,interfering viral replication and expression,inhibiting enzymes which are associated with virus replication,will provide ways for the screening of antitumor drugs. |
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| Keywords: | tumor virus neoplasms antitumor drugs viral replication enzyme |
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