| 大黄对多发伤合并休克兔肝、小肠保护机制的研究 |
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| 引用本文： | 喻安永,李建国,凌丽,杨光,马懿,陆元兰. 大黄对多发伤合并休克兔肝、小肠保护机制的研究[J]. 遵义医学院学报, 2008, 31(3): 233-237 |
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| 作者姓名： | 喻安永 李建国 凌丽 杨光 马懿 陆元兰 |
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| 作者单位： | 遵义医学院附属医院,急诊科,贵州,遵义,563003 |
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| 摘 要： | 目的观察大黄对多发伤合并休克兔肝、小肠的保护作用。方法纯种大白兔24只，复制多发性创伤合并休克免的模型，随机分为三组：治疗组（常规治疗＋大黄治疗组），对照组（常规治疗＋安慰治疗组），假手术组，每组8只。复苏24h后处死动物，取肝、小肠行病理检查，并测量细胞线粒体二维平面形态计量学参数和三维平面形态计量学参数。结果治疗组肝及小肠粘膜病理损害的程度较对照组明显减轻，细胞单位胞浆内治疗组比对照组线粒体数量多，肿胀较轻微。结论大黄能减轻多发伤合并休克后肝、小肠病理改变，大黄对多发伤合并休克模型兔肝、小肠损伤有显著保护作用。
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| 关 键 词： | 大黄 多发性创伤 休克 内脏 病理改变 |
Protective effect of Rhubarb on liver and small intestinal in multiple traumatic rabbits with complicating shock |
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| YU An-yong,LI Jian-guo,LING Li,YANG Guang,MA Yi,LU Yuan-lan. Protective effect of Rhubarb on liver and small intestinal in multiple traumatic rabbits with complicating shock[J]. Acta Academiae Medicine Zunyi, 2008, 31(3): 233-237 |
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| Authors: | YU An-yong LI Jian-guo LING Li YANG Guang MA Yi LU Yuan-lan |
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| Affiliation: | YU An-yong,LI Jian-guo,LING Li,YANG Guang,MA Yi,LU Yuan-lan. (Department of Emergency,The First Affiliated Hospital of Zunyi Medical College,Guizhou Zunyi 563003,China) |
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| Abstract: | Objective To observe the protective effect of Rhubarb on liver and small intestinal in multiple traumatic rabbits with complicating shock. Methods Twenty four rabbits were randomly divided into 3 groups, 8 in each group, namely sham operation group, treatment with Rhubarb group(treatment group),treatment with normal saline group(control group). multiple traumatic rabbits with complicating shock animal model was established according to the Chen's method. 24 hours after seriously multiple trauma the animals ... |
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| Keywords: | Rhubarb multiple trauma shock viscera pathological change |
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