| 恶性滋养细胞肿瘤预后因素的多元分析 |
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| 引用本文： | 刘毅智,张琼英. 恶性滋养细胞肿瘤预后因素的多元分析[J]. 中南大学学报(医学版), 1996, 0(5) |
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| 作者姓名： | 刘毅智 张琼英 |
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| 作者单位： | Department of Obstertrics and Gynecology，The Second Affiliated Hospital，Hunan Medical University |
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| 摘 要： | 对１２７例恶性滋养细胞肿瘤患者的１０项预后因素进行分析。结果显示：绒癌病死率为２６．７％（１６／６０）明显高于侵蚀性葡萄胎的病死率１．５％（１／６７）。单变量分析有７项因素对预后有意义，多变量分析只有肝脑及全身转移（ＲＲ＝５２．５，Ｐ＜０．０１）和对初次化疗反应差（ＲＲ＝５２．７，Ｐ＜０．０１）两项因素有意义。提示临床病理诊断为绒癌和以上两项是重要的预后不良因素。
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| 关 键 词： | 滋养层肿瘤，预后，因素分析，统计学，多元分析 |
A MULTIVARIATE ANALYSIS OF PKOGNOSTIC FACTORS IN NMALIGNANT TROPHOBLASTIC TUMORS |
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| Liu Yizhi,Zhang Qiongying. A MULTIVARIATE ANALYSIS OF PKOGNOSTIC FACTORS IN NMALIGNANT TROPHOBLASTIC TUMORS[J]. Journal of Central South University. Medical sciences, 1996, 0(5) |
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| Authors: | Liu Yizhi Zhang Qiongying |
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| Abstract: | en prognostic factors of 127 patients with malignant trophoblastic tumors were evaluatedstatistically.The results showed that the 5-Vear survival rate was 85.6%.The mortality rate ofchoriocarcinoma was 26.17%(16/60),which was significantly higher than that of invasive mole1.5%(1/67).Using a univariate analysis,the following factors including duration of disease,an-tecedent pregnancy, the site and the number of metastasis,number of metastatic organs,clinico-pathologic diagnosis and response to primary chemotherapy were significant for prognosis,How-ever, using Cox regression analysis,only two factors were significant:(1) metastatic sites be-sides the the lungs and vagina(RR =52.5 P<0.01)2)resistance to primary chemotherapy(RR =52.7 P <0.01).It suggests that the previous two factors,together with choriocarcinomaare important factors of poor prognosis. |
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| Keywords: | trophoblastic tumor prognosis factor analysis statistical multivariateanalysis |
| 本文献已被 CNKI 等数据库收录！ |
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