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The use of oscillatory signals in the study of genetic networks
Authors:Lipan Ovidiu  Wong Wing H
Affiliation:Center for Biotechnology and Genomic Medicine, Medical College of Georgia, 1120 15th Street, CA-4124, Augusta, GA 30912, USA. olipan@mail.mcg.edu
Abstract:The structure of a genetic network is uncovered by studying its response to external stimuli (input signals). We present a theory of propagation of an input signal through a linear stochastic genetic network. We found that there are important advantages in using oscillatory signals over step or impulse signals and that the system may enter into a pure fluctuation resonance for a specific input frequency.
Keywords:systems biology   synthetic biology   stochastic processes
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