The use of oscillatory signals in the study of genetic networks |
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Authors: | Lipan Ovidiu Wong Wing H |
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Affiliation: | Center for Biotechnology and Genomic Medicine, Medical College of Georgia, 1120 15th Street, CA-4124, Augusta, GA 30912, USA. olipan@mail.mcg.edu |
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Abstract: | The structure of a genetic network is uncovered by studying its response to external stimuli (input signals). We present a theory of propagation of an input signal through a linear stochastic genetic network. We found that there are important advantages in using oscillatory signals over step or impulse signals and that the system may enter into a pure fluctuation resonance for a specific input frequency. |
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Keywords: | systems biology synthetic biology stochastic processes |
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