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依达拉奉治疗急性脑出血的临床观察
引用本文:赵嘉林. 依达拉奉治疗急性脑出血的临床观察[J]. 中国现代应用药学, 2006, 0(Z1)
作者姓名:赵嘉林
作者单位:浙江省宁波市李惠利医院神经内科 浙江宁波315000
摘    要:目的观察依达拉奉治疗急性脑出血的治疗效果和安全性。方法36例急性脑出血患者随机均分为治疗组和对照组,对照组按急性脑出血常规治疗,治疗组在常规治疗的基础上,给予依达拉奉治疗。两组均于治疗前及治疗后第14天分别进行神经功能缺损量表(CSS)评定,并观察依达拉奉治疗期间不良反应。结果两组治疗14天后,CSS评分均有改善,但治疗组明显低于对照组(21.2±10.4 vs 24.6±9.3)(P<0.05),且依达拉奉治疗期间无明显副作用发生。结论依达拉奉可促进脑出血患者的神经功能康复并较为安全。

关 键 词:依达拉奉  脑出血  自由基  临床研究

Clinical Efficacy of Edaravone on Acute Cerebral Hemorrhage
ZHAO Jia-lin. Clinical Efficacy of Edaravone on Acute Cerebral Hemorrhage[J]. The Chinese Journal of Modern Applied Pharmacy, 2006, 0(Z1)
Authors:ZHAO Jia-lin
Abstract:OBJECTIVE To observe the efficacy and safety of edaravone in treatment of acute cerebral hemorrhage.METHODS 36 cases were randomly divided into a therapy group and a control group.The control group was given a routine treatment of acute ischemic hemorrhage.The therapy group was treated with edaravone in addition to the routine treatment received by the control group.Chinese stroke scale(CSS) in the two group were assessed at different time points before treatment and 14days after treatment.The changes of adverse reaction associated with the edaravone treatment were also observed. RESULTS After 14-day treatment,the result of CSS of two groups improved,and there was significant difference between the therapy group and control group(21.2 10.4 VS 24.6 9.3)(p<0.05).And there was no obvious adverse reaction of the edaravone treatment.CONCLUSION Edaravone can accelerate the recovery of neural function after cerebral hemorrhage safely.
Keywords:Edaravone  Cerebral hemorrhage  Free radical  Clinical research
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