大柴胡汤加减辅助治疗重症肺炎临床研究

目的:观察大柴胡汤加减辅助治疗重症肺炎的临床疗效。方法:将重症肺炎患者70例随机分为对照组和研究组,各35例。对照组给予注射用哌拉西林钠他唑巴坦钠、注射用美罗培南等常规治疗,研究组在对照组的基础上加用大柴胡汤加减治疗。2组疗程均为7 d,观察患者退热时间、咳嗽消失时间、气促消失时间、肺部湿啰音消失时间,以及治疗前后白细胞(WBC)、C-反应蛋白(CRP)、降钙素原(PCT)水平变化。结果:治疗前,研究组WBC、CRP、PCT水平与对照组比较,差异无统计学意义(P>0.05)。治疗后,研究组WBC、CRP、PCT水平改善及临床症状改善时间均优于对照组,差异有统计学意义(P<0.05)。结论:大柴胡汤加减辅助治疗重症肺炎优于常规医药治疗,能够改善患者的炎症反应,缓解临床症状,促进病情的好转。

Clinical Study on Modified Dachaihu Tang in Adjuvant Treatment of Severe Pneumonia

Objective:To observe the clinical effect of modified Dachaihu tang in adjuvant treatment of severe pneumonia.Methods:A total of 70 cases of patients with severe pneumonia were randomly divided into the control group and the study group, 35 cases in each group. The control group was given routine treatment with Piperacillin Sodium and Tazobactam Sodium for Injection and Meropenem for Injection,and the study group was additionally treated with modified Dachaihu tang based on the treatment of the control group. Both groups were treated for seven days. The changes in the levels of white blood cells(WBC),C-reactive protein(CRP),and procalcitonin(PCT) before and after treatment,the antipyretic time,and the disappearance time of coughing, panting and pulmonary moist rales were observed. Results: After treatment, the antipyretic time and the disappearance time of coughing,panting and pulmonary moist rales in the study group were shorter than those in the control group,the difference being significant(P<0.05). After treatment,the levels of WBC,CRP and PCT in the two groups were decreased when compared with those before treatment(P<0.05),and the above levels in the study group were lower than those in the control group(P<0.05). Conclusion: The therapy of modified Dachaihu tang combined with routine western medicine for severe pneumonia has significant curative effect and can effectively improve inflammatory responses in patients and quickly relieve the clinical symptoms,whose curative effect is better than that of simple western medicine.