房性心肌病与不明原因栓塞性卒中

不明原因栓塞性卒中（embolic stroke of undetermined source，ESUS）是卒中的一种亚型，约占缺血性卒中30%。房性心肌病是用来描述心房结构、功能和电异常的一种病理生理学概念，目前研究显示房性心肌病患者可能先于房颤发生，亦可形成血栓进而引起血栓栓塞，故被认为是ESUS的一种潜在机制。该综述将讨论房性心肌病及ESUS的概念、机制及关联，以及二者与房颤之间的转化关系，旨在促进对于房性心肌病与ESUS的概念、病理生理学机制的理解，从而在临床上更好地管理ESUS患者。

Atrial cardiomyopathy and embolic stroke of undetermined source

Embolic stroke of undetermined source (ESUS), a subtype of stroke, is accountable for around 30% of ischemic stroke. Atrial cardiomyopathy is a pathophysiological concept used to describe atrial structure, function, and electrical abnormalities. Atrial cardiomyopathy can occur before atrial fibrillation, and is also responsible for thrombogenesis and thromboembolism, so it is considered to be a potential mechanism of ESUS. This review aims to discuss the concepts, mechanisms, and associations of atrial cardiomyopathy and ESUS, as well as the conversion relationship among the atrial cardiomyopathy and ESUS and atrial fibrillation, to better understand the pathophysiological mechanisms of atrial cardiomyopathy and promote the management of these patients in clinical practices.