| 干细胞对外周神经损伤与肌肉萎缩的治疗进展 |
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| 引用本文： | 马萌萌,唐文洁.干细胞对外周神经损伤与肌肉萎缩的治疗进展[J].同济大学学报(医学版),2021,42(1):116-122. |
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| 作者姓名： | 马萌萌 唐文洁 |
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| 作者单位： | 同济大学附属东方医院干细胞转化医学产业基地,上海200123;同济大学附属东方医院干细胞转化医学产业基地,上海200123； 同济大学附属东方医院转化医学研究中心,上海200120 |
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| 基金项目： | 张江国家自主创新示范区专项发展资金重大专项（ZJ2018-ZD-004） |
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| 摘 要： | 外周神经损伤(peripheral nerve injury,PNI)是临床常见创伤,可引起失神经性肌肉萎缩,甚至永久性骨骼肌功能丧失.虽然外周神经损伤后在一定程度上能够再生,但伴随发生的骨骼肌功能丧失较难完全恢复.本文对PNI后神经和肌肉损伤的发生、发展及干细胞治疗的研究等进行综述,为临床提供研究方向和治疗选择.
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| 关 键 词： | 外周神经损伤 创伤 肌肉萎缩 再生 干细胞治疗 |
| 收稿时间： | 2020/4/3 0:00:00 |
Stem cells in treatment of peripheral nerve injury and muscle atrophy |
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| MA Meng-meng,TANG Wen-jie.Stem cells in treatment of peripheral nerve injury and muscle atrophy[J].Journal of Tongji University(Medical Science),2021,42(1):116-122. |
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| Authors: | MA Meng-meng TANG Wen-jie |
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| Abstract: | Peripheral nerve injury (PNI) is a common clinical trauma, which can induce denervated muscle atrophy and even permanent skeletal muscle loss. Although peripheral nerves can regenerate to a certain extent, the accompanying loss of skeletal muscle function is difficult to recover completely. This article reviews the development, progression of PNI, and stem cell therapy for nerve and muscle injury to provide information for research and treatment of PNI. |
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| Keywords: | peripheral nerve injury trauma muscle atrophy regeneration stem cell therapy |
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