低管电压联合高浓度低流率对比剂注射方案颈动脉CTA的可行性分析

目的:分析颈动脉CT血管成像检查中采用低管电压联合高浓度、低流率对比剂注射方案的可行性.方法:前瞻性将430例拟行颈动脉CTA检查的患者随机分为两组:A组215例,使用对比剂碘美普尔(400 mg I/mL)45 mL,注射流率为4 mL/s,管电压为100 kV;B组215例,注射碘帕醇(370 mg I/mL)65...

Feasibility analysis of low-tube voltage combined with high-concentration contrast medium and low-flow-rate injection in carotid CT angiography

Objective:To analyze the feasibility of low tube voltage combined with high concentration contrast medium and low-flow-rate injection in carotid artery CT angiography.Methods:430 patients planned to carotid CT angiography were prospectively collected and randomly divided into group A and group B.215 patients in group A received 45mL iomeprol(400mg I/mL)injected at a flow rate of 4mL/s,and the tube voltage was 100kV;and 215 patients in group B were administrated 65mL iopamidol(370mg I/mL)at a flow rate of 5mL/s,and a tube voltage of 120kV was used.On CTA images of each patients,CT values of the aortic arch,common carotid artery,and internal and external carotid artery were measured,and the effective radiation dose(ED),signal-to-noise ratio(SNR),and contrast-to-noise ratio(CNR)were calculated.The difference of the index above mentioned between the two groups was analyzed using chi-square test and t-test.Results:There was no significant diffe-rence in CT values of the aortic arch,common carotid artery,internal and external carotid artery between the two groups(all P>0.05);the ED of group A and B were(2.57±0.10)and(6.50±0.23)mSv,the ED of group A was significantly reduced compared with group B(P<0.05).The SNR of the two groups were 13.23±1.37 and(13.07±1.41),with no statistical difference(P>0.05);the CNR of the two groups were 10.61±1.05 and 10.55±1.26,with no statistical difference(P>0.05).The difference of the incidence of contrast agent extravasation between the two groups was statistically significant(P<0.05).Conclusion:The scheme of low tube voltage combined with high concentration of contrast medium and low-flow-rate injection can reduce the effective radiation dose on the basis of ensuring the image quality of carotid CT angiography.At the same time,the application of low flow rate injection reduces the risk of contrast medium extravasation.