| 中药桔梗研究进展及其质量标志物预测初步分析 |
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| 引用本文： | 许伟辰,罗子宸,谢彤,狄留庆,郭青,单进军. 中药桔梗研究进展及其质量标志物预测初步分析[J]. 南京中医药大学学报, 2021, 37(2): 294-302. DOI: 10.14148/j.issn.1672-0482.2021.0294 |
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| 作者姓名： | 许伟辰 罗子宸 谢彤 狄留庆 郭青 单进军 |
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| 作者单位： | 南京中医药大学中医儿科学研究所,江苏省儿童呼吸疾病(中医药)重点实验室,江苏南京 210023;南京中医药大学中医儿科学研究所,江苏省儿童呼吸疾病(中医药)重点实验室,江苏南京 210023;江苏省中药高效给药系统工程中心,江苏南京 210023;江苏省中药高效给药系统工程中心,江苏南京 210023;江苏省食品药品监督检验研究院,江苏南京 210008 |
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| 基金项目： | 国家自然科学基金(81774156);江苏省“六大人才高峰”高层次人才选拔培养资助项目(YY-022);江苏高校优势学科(中医学)建设工程资助项目(PAPD)。 |
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| 摘 要： | 桔梗是桔梗科植物桔梗Platycodon grandiflorum(Jacq.)A.DC的干燥根,主要含有皂苷、黄酮、多糖、甾醇和脂肪酸等化学成分,现代研究表明其具有祛痰止咳、抗炎、抗肿瘤、降血糖、抗肥胖、免疫调节等药理作用.从桔梗化学成分、药理作用、体内过程、毒性及溶血性和质量标准等5个方面进行了系统综述,并对其质量...
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| 关 键 词： | 桔梗 化学成分 药理活性 质量标志物 |
| 收稿时间： | 2020-11-15 |
Advance in Research on Platycodonis Radix and Preliminary Analysis of Its Quality Marker Prediction |
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| XU Wei-chen,LUO Zi-chen,XIE Tong,DI Liu-qing,GUO Qing,SHAN Jin-jun. Advance in Research on Platycodonis Radix and Preliminary Analysis of Its Quality Marker Prediction[J]. Journal of Nanjing University of Traditional Chinese Medicine(Natural Science), 2021, 37(2): 294-302. DOI: 10.14148/j.issn.1672-0482.2021.0294 |
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| Authors: | XU Wei-chen LUO Zi-chen XIE Tong DI Liu-qing GUO Qing SHAN Jin-jun |
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| Affiliation: | 1.Jiangsu Key Laboratory of Pediatric Respiratory Disease, Institute of Pediatrics, Nanjing University of Chinese Medicine, Nanjing, 210023, China2.Jiangsu Engineering Research Center for Efficient Delivery System of TCM, Nanjing, 210023, China3.Jiangsu Institute for Food & Drug Control, Nanjing, 210008, China |
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| Abstract: | Platycodonis Radix is the dried root of Platycodon grandiflorum(Jacq.)A.DC,which mainly contains saponins,flavonoids,polysaccharides,sterols and fatty acids.Modern studies have shown that Platycodonis Radix has pharmacological effects such as expectant and cough relieving,anti-inflammatory,anti-tumor,hypoglycemic,anti-obesity and immunoregulation.In this paper,the chemical constituents,pharmacological activities,in vivo process,toxicity,hemolysis and quality standard of Platycodonis Radix were systematically reviewed,and the quality markers of Platycodonis Radix were also discussed,in order to provide reference for further research and development of Platycodonis Radix. |
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| Keywords: | Platycodonis Radix chemical composition pharmacological activities Q-marker |
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