| 载药微球经导管动脉化疗栓塞治疗肝细胞癌研究进展 |
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| 引用本文： | 吴天慧,谢锋,韩梦月. 载药微球经导管动脉化疗栓塞治疗肝细胞癌研究进展[J]. 中国介入影像与治疗学, 2021, 18(3): 175-178 |
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| 作者姓名： | 吴天慧 谢锋 韩梦月 |
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| 作者单位： | 辽宁省人民医院核医学科, 辽宁 沈阳 110016 |
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| 摘 要： | 载药微球经导管动脉化疗栓塞(DEB-TACE)利用微球在靶病灶内释放化学治疗(简称化疗)药物,使靶肿瘤内药物浓度更高,而全身化疗药物浓度及不良反应降低;且微球可较完全栓塞肿瘤毛细血管网,闭塞肿瘤邻近血管,致癌细胞缺血、缺氧而坏死。本文对DEB-TACE治疗肝细胞癌(HCC)研究进展进行综述。
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| 关 键 词： | 癌,肝细胞 化疗栓塞,治疗性 载药微球 |
| 收稿时间： | 2020-07-25 |
| 修稿时间： | 2021-01-12 |
Advances of drug-eluting bead transcatheter arterial chemoembolization for treatment of hepatocellular carcinoma |
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| WU Tianhui,XIE Feng,HAN Mengyue. Advances of drug-eluting bead transcatheter arterial chemoembolization for treatment of hepatocellular carcinoma[J]. Chinese Journal of Interventional Imaging and Therapy, 2021, 18(3): 175-178 |
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| Authors: | WU Tianhui XIE Feng HAN Mengyue |
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| Affiliation: | Department of Nuclear Medicine, Liaoning Provincial People''s Hospital, Shenyang 110016, China |
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| Abstract: | Drug-eluting bead transcatheter arterial chemoembolization (DEB-TACE) uses microspheres to release chemotherapeutic agents within the target lesions, in order to achieve high drug concentration in the target tumor and low systemic chemotherapy drug concentration and adverse reactions. In addition, the capillary network of tumor can be completely embolized and the adjacent blood vessels of tumor occluded using microspheres, resulting hepatocellular carcinoma (HCC) cells necrotic due to ischemia and hypoxia. The advances of DEB-TACE in treatment HCC were reviewed in this article. |
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| Keywords: | carcinoma, hepatocellular chemoembolization, therapeutic drug-eluting beads |
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