(1) Department of Urology, Ichihara Hospital, Teikyo University School of Medicine, 3426-3, Anesaki, Ichihara 299-0111, Japan;(2) Department of Urology, Faculty of Medicine, Toyama Medical and Pharmaceutical University, Toyama, Japan
Abstract:
To clarify whether serum levels of interleukin-11 (IL-11) could be a useful marker in patients with prostate cancer, serum IL-11 was determined in 73 and 23 men with prostate cancer and benign prostate hyperplasia (BPH), respectively, before treatment. There were no statistical differences of IL-11 levels between patients with prostate cancer and BPH. Patients with hormone-resistant prostate cancer had a significantly higher level of IL-11 than those with untreated cancer. Serum IL-11 levels may be a potential tumor marker for prostate cancer progression.