| 慢性非细菌性前列腺炎动物模型研究进展 |
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| 引用本文： | 钱伯初,史红,郑晓亮. 慢性非细菌性前列腺炎动物模型研究进展[J]. 中国临床药理学与治疗学, 2007, 12(1): 14-18 |
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| 作者姓名： | 钱伯初 史红 郑晓亮 |
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| 作者单位： | 1. 浙江省医学科学院药物研究所,杭州,310013,浙江;浙江大学城市学院药物研究所,杭州,310015,浙江
2. 浙江省医学科学院药物研究所,杭州,310013,浙江 |
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| 摘 要： | 慢性非细菌性前列腺炎是一种病因和发病机理未明、难于诊治的泌尿科常见病。研究制备的动物模型是阐明该病发病机理和开发新药的有效方法。因此，用作研究人类疾病的动物模型的有效性是选择动物模型最重要的标准，由于不同动物模型的不同特点，实验时应适当选择。本文就近年来慢性非细菌性前列腺炎动物模型的相关研究作简要综述。
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| 关 键 词： | 慢性非细菌性前列腺炎 动物模型 自身免疫 部分尿道阻塞 雌二醇 角叉菜胶 消痔灵注射液 大鼠 |
| 文章编号： | 1009-2501（2007）01-0014-05 |
| 收稿时间： | 2006-09-25 |
| 修稿时间： | 2006-10-14 |
Progress in research on animal models of chronic nonbacterial prostatitis |
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| QIAN Bo-chu,SHI Hong,ZHENG Xiao-liang. Progress in research on animal models of chronic nonbacterial prostatitis[J]. Chinese Journal of Clinical Pharmacology and Therapeutics, 2007, 12(1): 14-18 |
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| Authors: | QIAN Bo-chu SHI Hong ZHENG Xiao-liang |
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| Abstract: | Chronic nonbacterial prostatitis is a common urologic condition which is difficult to be treated effectively. Little is known about the etiology and pathogenesis of the disease. Preparation of the animal model of chronic nonbacterial prostatitis is an effective method to research the pathogenesis of the disease and development of new drug. Different animal models have distinctive traits, therefore, it is crucial to select suitable animalmodels for researching human diseases. In the review, the progress in the research on animal models of such disease is discussed. |
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| Keywords: | chronic nonbacterial prostatitis animal model autoimmune partial urethral obstruction rat etradiol carrageen |
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