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Elevated sleep arousal thresholds in enuretic boys: clinical implications
Authors:NM Wolfish  RT Pivik  KA Busby
Affiliation:Department of Pediatrics, Faculty of Medicine, University of Ottawa Nephrology Service, Children's Hospital of Eastern Ontario;Departments of Psychiatry and School of Psychology, University of Ottawa;Department of Psychiatry, University of Ottawa, Canada
Abstract:Enuretic children are described as difficult to arouse from sleep. We studied auditory sleep arousal thresholds in enuretic boys and report on die clinical implications of these findings. Fifteen enuretic and 18 control subjects (7–12-year-old males) were studied in a sleep laboratory for four consecutive nights using standard polysomnographic recording techniques. Sleep was undisturbed for the initial two nights and waking thresholds were measured on the following two nights. Enuretic children wet most frequently in the first two-thirds of the night. Arousal attempts were successful 39.7% of the time in controls and only 9.3% of the time in enuretics. In conclusion, enuretic males were more difficult to arouse than age-matched controls. The elevated arousal thresholds may be due to delayed maturation. Treatment programmes that rely on awakening should be aware of these features.
Keywords:Arousal thresholds    desmopressin    DDAVP    enuresis    treatment of enuresis    wet alarms
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