高血压合并阻塞性睡眠呼吸暂停低通气综合征中医证候的临床研究

目的:探讨高血压合并阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者的中医证候要素特点。方法:对64例入选的高血压合并OSAHS患者按照中医辨证进行证候要素分析,并分析其主要证候要素对呼吸紊乱指数(AHI)、爱泼沃斯嗜睡量表(ESS)评分及体重指数(BMI)的影响。结果:痰湿证、气虚证相对其他证候要素多见,分别为46例(71.9%)、39例(60.9%),其次为血瘀证16例(25.0%)。ESS评分、AHI的平均秩及BMI平均秩在有痰湿证、血瘀证的患者中显著增高(P0.05)。结论:痰湿证、气虚证是高血压合并OSAHS患者的常见证候要素,其次为血瘀证。BMI可作为高血压合并OSAHS痰湿证、血瘀证的一项评价指标。痰湿、血瘀会加重高血压合并OSAHS患者的各种主观症状、嗜睡程度。

Clinical Study on the Traditional Chinese Medicine Syndrome of Hypertension with Obstructive Sleep Apnea Hypopnea Syndrome

Objective:To study the characteristics of traditional Chinese medieine(TCM)syndrome of hypertensive patients combined with obstructive sleep apnea hypopnea syndrome(OSAHS).Methods:64 hypertensive patients with OSAHS was analysed by TCM syndrome,and the impacts on Apnea Hypopnea Index(AHI),Epworth Sleepiness Scale(ESS)and Body Mass Index(BMI)were analyzed.Results:The phlegm-damp syndrome and qi deficiency syndrome were more common than other syndromes,respectively had 46 patients(71.9%),39 patients(60.9%),and followed by blood stasis syndrome with 16 patients(25.0%).The AHI,ESS and BMI were statistically elevated among those with phlegm-damp syndrome or blood stasis syndrome(P<0.05).Conclusions:The phlegm-damp syndrome and qi deficiency syndrome were common in hypertensive patients with OSAHS,and followed by blood stasis.BMI can be used as a evaluate indicator for hypertension with OSAHS patients who have phlegm-damp and blood stasis syndrome.Phlegm-damp and blood stasis will aggravate subjective symptoms and the intensity of sleeping.