中医膳食调节对慢性肾功能衰竭的临床研究

目的:探讨中医膳食调节对慢性肾功能衰竭的临床作用,为临床治疗慢性肾功能提供指导。方法:入选2007年8月-2010年12月就诊的慢性肾功能衰竭的患者96例,将所有患者随机分为观察组和对照组,每组48例,观察组给予中医膳食干预,对照组给予普通饮食。干预1个月后,比较两组患者临床疗效、肾功能改善情况。结果:在常规治疗的基础上,采用中医膳食进行干预组显效率和总有效率分别为64.6%、83.4%,而对照组显效率和总有效率分别为47.9%、72.9%,差异具有统计学意义(P0.05)。两组患者干预后临床表现均较干预前显著改善,各种症状的评分较治疗前显著降低,差异具有统计学意义(P0.05);采用中医膳食干预后临床症状改善更加显著,治疗后评分显著低对照组治疗后,差异具有统计学意义(P0.05)。两组患者干预后,肾功能均明显好转,血肌酐、血尿素氮均较干预前显著降低,差异具有统计学意义(P0.05);而内生肌酐清除率较干预前显著升高,差异具有统计学意义(P0.05);观察组改善更显著,干预后血肌酐、血尿素氮、内生肌酐清除率与对照组干预后差异有统计学意义(P0.05)。结论:中医膳食调节能显著改善患者的临床症状和肾功能,具有一定的临床意义。

Clinical Research of Traditional Chinese Medical Dietary for Chronic Renal Failure

Objective:To investigate the clinical effect of traditional Chinese medical dietary for chronic renal failure,providing guidance for the clinical treatment of chronic renal failure.Method:96 chronic renal failure patients were enrolled in our hospital from August 2007 to December 2010.They were divided into observation group and control group,48 patients in each group.The observation group was given traditional Chinese medical dietary and control group were given ordinary dietary.The clinical effect and renal function were compared in two groups before and after intervention.Results:The significant efficiency rate and total rate were 64.6%,83.4%;in observation group were 47.9%,72.9%,P<0.05.The clinical manifestation was improved in both groups,but it was more significantly in observation group than in control group,P<0.05.Renal function was improved after intervention in both groups.Blood creatinine and blood urea nitrogen were lower and creatinine clearance rate was higher than that before intervention,P<0.05.But in observation group,the indexes changed more obviously than those in control group,P<0.05.Conclusion:Traditional Chinese medical dietary can improve the clinical manifestation and renal function obviously,having certain clinical significance.