稳定控制血糖在防治湿热毒蕴型糖尿病足坏疽发生中的意义

目的:通过研究新发湿热毒蕴型糖尿病足坏疽与普通2型糖尿病无并发症患者临床血糖指标之间的差异;同时通过比较新发坏疽与治疗后坏疽血糖指标之间差异,说明稳定控制血糖在防治本病发生的重要性。方法:通过检测新发湿热毒蕴型糖尿病足坏疽患者(A组)、治疗超过3个月以上糖尿病足坏疽未痊愈患者(B组)及2型糖尿病无并发症患者(C组)的空腹血糖(FBG)、糖化血红蛋白(HbA1c)、糖化血清蛋白(GSP)的水平,然后对A组及C组、A组及B组之间就上述指标的平均值应用SPSS 17.0进行统计学分析。结果:2型糖尿病患者与新发糖尿病足湿热毒蕴型坏疽患者比较GSP有非常显著性差异(P0.01),HbA1c比较有显著性差异(P0.05)。新发湿热毒蕴型糖尿病足坏疽与治疗超过3个月以上糖尿病足坏疽患者比较GSP有非常显著性差异(P0.01),HbA1c比较有显著性差异(P0.05)。结论:GSP、HbA1c可以作为监控糖尿病病情变化的重要依据,2～3周高血糖水平即可能增加湿热毒蕴型糖尿病足坏疽的危险性,说明稳定控制血糖对防治本病发生具有重要临床使用价值。

Significance of Stable Blood Glucose Levels Control in the Prevention and Treatment of Foot Gangrene due to Dampness-Heat Poisoning Syndrome Diabetes

Objective:Through the research of clinical glucose condition differences between foot gangrene patients due to the new attack dampness-heat poisoning syndrome diabetes and type 2 diabetic patients without complications;at the same time,comparing the glucose differences between new attack gangrene patients and gangrene patients who had been treated,discussion on the value of controlling blood sugar stable in order to prevent foot gangrene due to dampness-heat poisoning syndrome diabetes was made.Methods:Through testing the FBG,HbA1c and GSP of the following 3 groups:new attack dampness-heat poisoning syndrome diabetes foot gangrene patients(group A),dampness-heat poisoning syndrome diabetes foot gangrene patients who have been treated by more than 3 months were not fully cured(group B),type 2 diabetes patients with no complications(group C),statistical software SPSS 17.0 was used to compare the mean values of every teams.Results:Group A and C were compared with a very significant difference between the GSP(P<0.01),HbA1c was significantly different(P<0.05).Conclusion:GSP and HbA1c level can be used as important diabetes indexes to master the condition changes,high blood sugar levels in 2~3 weeks may increase the risk of foot gangrene duet dampness-heat poisoning syndrome diabetes.There is an important clinical value as the signal of diabetes foot gangrene.