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正交试验优化左金分散片的乙醇提取工艺
引用本文:曾彬,高剑坤,任劲松,夏清. 正交试验优化左金分散片的乙醇提取工艺[J]. 北方药学, 2012, 0(10): 25+67-25,67
作者姓名:曾彬  高剑坤  任劲松  夏清
作者单位:四川中医药高等专科学校
摘    要:目的:优化左金分散片的乙醇提取工艺。方法:以吴茱萸碱、吴茱萸次碱的提取率为指标,采用L9(3)4正交试验法对左金分散片的乙醇提取工艺进行优选。结果:左金分散片乙醇提取的最佳工艺路线为:加5倍量80%乙醇,回流提取3次,每次1.5小时。结论:该提取工艺简单可行,提取率高,适于工业生产。

关 键 词:左金分散片  正交试验  乙醇提取

Orthogonal experiment for optimization of the alcohol extraction technology of Zuojin dispersible tablets
Zeng Bin Gao Jiankun Ren Jinsong Xia Qing. Orthogonal experiment for optimization of the alcohol extraction technology of Zuojin dispersible tablets[J]. BEIFANG YAOXUE, 2012, 0(10): 25+67-25,67
Authors:Zeng Bin Gao Jiankun Ren Jinsong Xia Qing
Affiliation:Zeng Bin Gao Jiankun Ren Jinsong Xia Qing(Sichuan college of Traditional Chinese Medicine,Mianyang 621000,Sichuan,China)
Abstract:Objective:Optimization of alcohol extraction technology of Zuojin dispersible tablets. Methods: To vodiamine and rutaecarpine for index,use L9(3)4 orthogonal test on alcohol extraction process of Zuojin dispersible tablets.Results:The optimum ethanol extraction route of Zuojin dispersible tablets:with 5 times of water,extract 3 times,each time 1.5 hours.Conclusions:The extraction process is simple and feasible,with high extraction rate,and is suitable for industrial production.
Keywords:Zuojin dispersible tablets Orthogonal experiment Ethanol extraction
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