降钙素原与乳酸在老年社区获得性肺炎患者预后评估中的应用

目的研究降钙素原(PCT)与乳酸对老年社区获得性肺炎患者的病情和预后的评估作用。方法 118例老年社区获得性肺炎患者,入院后给予PCT、乳酸等检查,并给予肺炎严重指数(PSI)评分。分别比较重症与非重症肺炎、死亡组和存活组PCT、乳酸和PSI的区别;分析PCT、乳酸与PSI的相关性。结果重症肺炎患者乳酸、PCT和PSI评分均大于非重症患者,死亡组乳酸、PCT和PSI评分均大于存活组(P<0.05);乳酸、PCT与PSI评分呈正相关(r=0.63,0.65,P<0.05)。结论 PCT和乳酸对老年社区获得性肺炎患者的预后和病情有评估作用,PCT和乳酸升高提示患者预后差。

Application of procalcitonin and lactate in the evaluation of prognosis of elderly patients with community acquired pneumonia

Objective To evaluate the function of lactate and procalcitonin （PCT） in the prognosis of elderly patients with com- munity acquired pneumonia （CAP）. Methods 118 cases of elderly CAP patients were selected to examine their PCT, lactate and pneu- monia severity index （PSI） score. PCT and PSI scores were compared between the death group and the survival group, as well as the se- vere pneumonia group and non-severe pneumonia group. The relationship between the content of lactate and PCT and PSI score was ana- lyzed. Results The levels of PCT and lactate and PSI scores were higher in the severe pneumonia group and the death group than in the non-severe pneumonia group and the survival group （ P 〈 0.05 ）. There was a positive correlation between PSI scores and the levels of lac- tate and PCT （ r = 0.63, 0. 65, P 〈 0. 05 ）. Conclusion The levels of lactate and PCT have certain prognostic evaluation function for elderly patients with CAP, and the high levels of lactate and PCT suggest a poor prognosis.