Ocular Adnexal Lymphoma: no evidence for bacterial DNA associated with lymphoma pathogenesis |
| |
| Authors: | Matthews Julie M Moreno Lilliana I Dennis Jeremy Byrne Gerald E Ruiz Phillip Dubovy Sander R Lossos Izidore S |
| |
| Institution: | Sylvester Comprehensive Cancer Center, Division of Hematology-Oncology, Department of Medicine, University of Miami;, Department of Molecular and Cellular Pharmacology, University of Miami;, Department of Chemistry, Florida International University;, Department of Pathology, University of Miami;, and Department of Pathology, Bascom Palmer Eye Institute, University of Miami, Miami, FL, USA |
| |
| Abstract: | Ocular Adnexal Lymphomas (OALs) are the most common tumors of the eye, the majority being extranodal mucosa-associated lymphoid tissue (MALT) lymphomas. Association with Chlamydia psittaci was described in some geographic areas. OAL response to antibiotic therapy was reported in cases not harboring Chlamydia psittaci DNA, suggesting that other bacterial infection might be implicated in the pathogenesis. We examined 49 MALT OALs for bacterial DNA using two distinct polymerase chain reaction techniques based on universal bacterial primers. No bacterial DNA that could be implicated in OAL pathogenesis was detected, suggesting that bacterial infection is not associated with OAL in South Florida. |
| |
| Keywords: | ocular adnexal lymphoma MALT Chlamydia |
| 本文献已被 PubMed 等数据库收录！ |
|
