| 我院β-内酰胺类抗生素致不良反应442例分析 |
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| 引用本文： | 韩燕,陈娟,韩勇. 我院β-内酰胺类抗生素致不良反应442例分析[J]. 中国药房, 2006, 17(7): 528-529 |
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| 作者姓名： | 韩燕 陈娟 韩勇 |
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| 作者单位： | 1. 华中科技大学附属协和医院药剂科,武汉市,430022
2. 武汉大学医学院,武汉市,430060 |
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| 摘 要： | 目的:了解β-内酰胺类抗生素药物致药品不良反应(ADR)的发生特点,促进临床合理用药。方法:对我院2001年~2005年收集到的442例β-内酰胺类抗生素ADR报告进行回顾性分析。结果:5年间共有961例ADR报告,其中由β-内酰胺类抗生素引起的ADR占总例数的46%;ADR表现以皮肤及附件损伤最为常见,其次为心血管系统、消化系统等。结论:应促进β-内酰胺类抗生素药物的合理使用,并重视ADR的监测工作,以减少或避免ADR的发生。
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| 关 键 词： | β-内酰胺 抗生素 药品不良反应 合理用药 分析 |
| 文章编号： | 1001-0408(2006)07-0528-02 |
| 收稿时间： | 2005-11-17 |
| 修稿时间： | 2006-02-21 |
Adverse Drug Reactions Induced by β- Lactam Antibiotics:Survey of 442 Cases |
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| HAN Yan,CHEN Juan,HAN Yong. Adverse Drug Reactions Induced by β- Lactam Antibiotics:Survey of 442 Cases[J]. China Pharmacy, 2006, 17(7): 528-529 |
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| Authors: | HAN Yan CHEN Juan HAN Yong |
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| Affiliation: | 1. Dept.of Pharmacy, The Affiliated Xiehe Hospital of Central China Technical University, Wuhan 430022, China;2. Medical College of Wuhan University,Wuhan 430060, China |
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| Abstract: | OBJECTIVE:To study the adverse drug reactions induced byβ-lactam antibiotics and to promote rational use of drugs in clinics.METHODS:442ADR cases induced byβ-lactam antibiotics collected in our hospital during2001～2005were analyzed retrospectively.RESULTS:Among the total961ADR cases collected in5years,46%were induced byβ-lactam antibiotics.The most common displays of ADR were the lesion of skin and the appendants,followed by the lesion of cardiovas-cular system and digestive system etc.CONCLUSION:It is advisable to promote rational use ofβ-lactam antibiotics and strengthen ADR monitoring so as to decrease or avoid the occurrence of ADR. |
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| Keywords: | β-lactam Antibiotics Adverse drug reaction Rational administration Analysis |
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