An immunohistologic characterization of human prostatic atypical hyperplasia |
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| Authors: | P. Chou V. Ray M. Shaw M. Rubenstein P. Guinan |
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| Affiliation: | (1) Hektoen Institute for Medical Research, Chicago, Illinois, USA;(2) Division of Pathology of the Cook County Hospital, Chicago, Illinois, USA;(3) Division of Urology of the Cook County Hospital, Chicago, Illinois, USA;(4) Department of Urology, Rush Presbyterian St. Lukes Medical Center, Chicago, Illinois, USA;(5) Department of Biochemistry, Rush Presbyterian St. Lukes Medical Center, Chicago, Illinois, USA |
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| Abstract: | Summary In an effort to better distinguish the morphologic relationship of atypical hyperplasia of the prostate to benign prostatic hypertrophy and prostatic cancer, 43 prostate specimens were analyzed with ten immunohistologic markers. Two cytokeratin antibodies appeared useful (Cyto M and Cyto P, with the latter slightly more discriminatory). In summary, it appears that atypical hyperplasia is immunohistopathologically related to both benign prostatic hypertrophy and prostatic cancer, having characteristics of both.This research was generously supported in part by the American Cancer Society (RCF-86-117), the AMOCO Foundation, the Blum-Kovler Foundation, The Cancer Federation and the Julius Frankel Foundation |
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| Keywords: | Benign prostatic hypertrophy Prostatic atypical hyperplasia Adenocarcinoma of the prostate Immunohistopathology |
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